Sedation dentists are a select group of individuals who make up only 3-5% of the general dentist populations. One of the hurdles that sedation dentists have is understanding what drugs and medications we can use, should we use, and what would be most effective in managing the conditions we are trying to treat. There are hundreds of medications to choose from and many medications used by dentists are misused based on improper training techniques, misunderstanding of pharmacology and old schools of thought. After training hundreds of dentists, performing thousands of sedation cases, and building a successful sedation practice it became more evident that the world of sedation dentists needed a book such as this. This book highlights a narrow group of medications, which are safe, easy to use, and highly effective in treating the conditions that are specific to the sedation dentist’s needs. This is the ultimate medication handbook to help guide sedation dentists.